贺海波,彭静维,范丽鹏,齐立军,高伟,武耐英

• 1:河北工程大学材料科学与工程学院
• 2:晨光生物科技集团股份有限公司
• 3:河北省植物资源综合利用重点实验室

摘要(Abstract)：

采用动态法测定了278.15～323.15 K范围内双脱甲氧基姜黄素晶体在不同浓度乙醇中的溶解度，并用修正的Apelblat方程对溶解度数据进行拟合。使用Van't Hoff方程计算双脱甲氧基姜黄素晶体在不同浓度乙醇中溶解吉布斯自由能ΔG、溶解焓ΔH和溶解熵ΔS,并在90%乙醇中进行了降温结晶实验。结果表明，双脱甲氧基姜黄素在不同浓度乙醇中的溶解度随温度的升高而明显增加，修正的Apelblat方程拟合效果良好。使用90%乙醇作为溶剂的降温结晶得到的产品纯度在92%左右，收率大于70%。

关键词(KeyWords)： 双脱甲氧基姜黄素;溶解度;热力学;降温结晶

Abstract:

Keywords:

基金项目(Foundation): 邯郸市科学技术研究与发展计划项目(21422012320,22313014014)

作者(Author): 贺海波,彭静维,范丽鹏,齐立军,高伟,武耐英

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