鸟苷酸发酵工艺优化Optimization of the Fermentation Technology of GMPs
刘晨,丁长河,金少举,陈复生,杜娟
摘要(Abstract):
鸟苷酸具有显著的增鲜、辅助抗肿瘤、提高机体免疫力以及调节机体营养代谢等作用,因而广泛应用于食品和医药领域。发酵以枯草芽孢杆菌变异菌株为出发菌株,在单因素试验基础上,采用正交试验对发酵培养基及发酵条件对鸟苷产量的影响进行研究,结果表明:葡萄糖添加量为10%,发酵温度为36℃,发酵时间为72h时,鸟苷产量可达到10.6g/L,较优化前提高了71%。
关键词(KeyWords): 鸟苷酸;发酵;工艺
基金项目(Foundation): 中国博士后科学基金资助项目(2016M602244)
作者(Author): 刘晨,丁长河,金少举,陈复生,杜娟
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