汪璇,刘秀继,吴滢滢,陈晖,郑平,王伟平

• 1:湖北工业大学生命科学与健康工程学院
• 2:安琪酵母股份有限公司

摘要(Abstract)：

以红曲霉固态发酵体系为研究对象，探究乙酸盐对Monacolin K(MK)产量的影响，发现乙酸铵、乙酸钾和乙酸的添加均对红曲霉固态发酵MK的产量有促进作用，MK的产量分别提高到未添加乙酸盐时的1.52,1.24,1.14倍。0.5%乙酸铵对MK产量的促进作用最明显，MK产量为30.24 mg/g,开环率为80%,未检出桔霉素。低浓度的乙酸铵对红曲霉的生长有促进作用，乙酸铵的添加影响培养基最终pH值。pH值随着乙酸铵浓度的提高而逐渐升高，有利于部分内酯式MK转化为酸式MK,从而导致开环率提高，这些发现为利用红曲霉生产MK和开发具有功能性、保健性和安全性的红曲霉制品提供了重要参考。

关键词(KeyWords)： 红曲霉;乙酸铵;形态;Monacolin K

Abstract:

Keywords:

基金项目(Foundation): 国家自然科学基金资助项目(31101349)

作者(Author): 汪璇,刘秀继,吴滢滢,陈晖,郑平,王伟平

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