增鲜核苷酸代谢通路的研究进展Research Progress on Metabolic Pathway of Umami-Enhancing Nucleotides
谢姝瑶,张龙翼,刘怀玉,周良贵,蔡富杰,胡红玲,张崟
摘要(Abstract):
增鲜核苷酸是提升食品鲜味的关键物质之一,在改善食物风味中发挥着重要作用,这类物质与谷氨酸等鲜味剂协同增效,可以使食品的鲜味刺激提升数倍。由于增鲜核苷酸的天然来源有限、提取成本高、合成效率低等因素,严重制约了其规模化生产,亟待从代谢机制层面寻找优化路径。为此,文章在阐述增鲜核苷酸的理化特性的基础上,分析了增鲜核苷酸的生物合成机制、从头合成与补救合成路径,AMP、GMP间的相互转化及降解途径,梳理了代谢调控机制,包括关键酶的变构调控、代谢产物反馈抑制、基因表达调控及信号通路介导的动态调节。此外,探讨了环境因素如温度、pH值、金属离子等对代谢效率的影响,以期为呈味核苷酸代谢的精细调控和工业化生产提供参考。
关键词(KeyWords): 增鲜核苷酸;生物合成;代谢调控
基金项目(Foundation): 四川省自然科学基金项目(2024NSFSC0367)
作者(Author): 谢姝瑶,张龙翼,刘怀玉,周良贵,蔡富杰,胡红玲,张崟
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