食品用微生物的抑菌作用研究进展Research Progress on Antibacterial Effect of Food Microorganisms
刘琴琴,张楠,胡晓茵,廖娜,徐宁
摘要(Abstract):
食品的安全和健康是食品领域长久以来的研究重点,开发天然防腐抗菌化合物具有重要意义。食品用微生物的抑菌现象是一种普遍存在的天然微生物保护机制,可用来维持食品生态平衡、延长食品货架期、保障食品安全。文章重点论述了食品用微生物或其代谢产物对常见腐败菌和致病菌的抑制效应、抑菌机制以及食品用微生物抑菌技术在食品等工业领域的应用,为进一步探索食品用微生物的抑菌作用和机制,开发新型、高效、绿色的天然食品生物防腐保鲜技术提供了研究基础。
关键词(KeyWords): 食品用微生物;抑菌效应;抑菌机制
基金项目(Foundation): 湖北省重点研发计划项目(2023BBB010)
作者(Author): 刘琴琴,张楠,胡晓茵,廖娜,徐宁
参考文献(References):
- [1]Lucera A,Costa C,Conte A,et al.Food applications of natural antimicrobial compounds[J].Frontiers in Microbiology,2012,3:287.
- [2]Bourdichon F,Laulund S,Tenning P.A comparison of FIL-IDF/EFFCA inventory of microbial food culture and EFSA biohazard qualified presumption of safety[J].FEMS Microbiology Letters,2019.
- [3]Bourdichon F,Laulund S,Tenning P.Inventory of microbial species with a rationale:a comparison of the IDF/EFFCA inventory of microbial food cultures with the EFSA Biohazard Panel qualified presumption of safety[J].FEMS Microbiology Letters,2019,366(5):1093.
- [4]张彤,杨忠仁,张凤兰.食品天然防腐剂及其应用研究进展[J].中国调味品,2024,49(4):206-211.
- [5]Kaul S,Gupta S,Ahmed M,et al.Endophytic fungi from medicinal plants:a treasure hunt for bioactive metabolites[J].Phytochemistry Reviews,2012,11(4):487-505.
- [6]侯莎,吴昌正,童星.米曲霉的次级代谢调控研究进展[J].中国调味品,2021,46(6):196-200.
- [7]蒋利亚.米曲霉产曲酸菌种选育、发酵条件及抑菌研究[D].长沙:湖南农业大学,2012.
- [8]Choi D,Alshannaq A F,Bok Y,et al.Broad-spectrum antimicrobial activities of a food fermentate of Aspergillus oryzae[J].Microbiology Spectrum,2024,12(12):185424.
- [9]Tu Zepeng,Choi D,Chen Yuxing,et al.The food fermentation fungus Aspergillus oryzae is a source of natural antimicrobials against Listeria monocytogenes[J].Journal of Dairy Science,2025,108(4):3444-3454.
- [10]Cheng M J,Wu M D,Chen I S,et al.Chemical constituents from the fungus Monascus purpureus and their antifungal activity[J].Phytochemistry Letters,2011,4(3):372-376.
- [11]Patel S.Functional food red yeast rice (RYR) for metabolic syndrome amelioration:a review on pros and cons[J].World Journal of Microbiology & Biotechnology,2016,32(5):87.
- [12]Dhale M A,Javagal M,Puttananjaiah M H.Protective and antioxidative effect of rubropunctatin against oxidative protein damage induced by metal catalyzed reaction[J].International Journal of Biological Macromolecules,2018,116:409-416.
- [13]Husakova M,Orlandi V T,Bolognese F,et al.Screening antibacterial photodynamic effect of Monascus red yeast rice (Hong-Qu) and mycelium extracts[J].Current Microbiology,2024,81(7):183.
- [14]Zhao Guoping,Li Yingqiu,Yang Jie,et al.Antibacterial characteristics of orange pigment extracted from Monascus pigments against Escherichia coli[J].Czech Journal of Food Sciences,2016,34(3):197-203.
- [15]Feng Linhui,Li Yingqiu,Sun Guoxiang,et al.Antibacterial effect of orange Monascus pigment against Staphylococcus aureus[J].Acta Alimentaria,2019,48(2):169-176.
- [16]Majhi S,Dhale M A,Puttananjaiah M H.Inhibitory effect of Monascus purpureus pigment extracts against fungi and mechanism of action[J].Frontiers in Sustainable Food Systems,2023,7:1100961.
- [17]Behera B C.Citric acid from Aspergillus niger:a comprehensive overview[J].Critical Reviews in Microbiology,2020,46(6):727-749.
- [18]Park H S,Jun S C,Han K K,et al.Diversity,application,and synthetic biology of industrially important Aspergillus fungi[J].Advances in Applied Microbiology,2017,100:161-202.
- [19]Akinfala T O,Houbraken J,Sulyok M,et al.Moulds and their secondary metabolites associated with the fermentation and storage of two cocoa bean hybrids in Nigeria[J].International Journal of Food Microbiology,2020,316:108490.
- [20]Jomori T,Hara Y,Sasaoka M,et al.Mycobacterium smegmatis alters the production of secondary metabolites by marine-derived Aspergillus niger[J].Journal of Natural Medicines,2020,74(1):76-82.
- [21]Samson R A,Visagie C M,Houbraken J,et al.Phylogeny,identification and nomenclature of the genus Aspergillus[J].Studies in Mycology,2014,78:141-173.
- [22]Wei Longfeng,Ran Jiang,Li Zhu,et al.Chemical composition,antibacterial activity and mechanism of action of fermentation products from Aspergillus niger xj[J].Applied Biochemistry and Biotechnology,2024,196(2):878-895.
- [23]刘吴娟,陈青,郭金,等.黑曲霉菌丝体及发酵液抗菌活性初步研究[J].广东农业科学,2012,39(2):76-78.
- [24]史冰柯.黑曲霉La2对梨树腐烂病菌抑菌活性分析[D].北京:中国农业科学院,2024.
- [25]Singh V P.Recent approaches in food bio-preservation—a review[J].Open Veterinary Journal,2018,8(1):104-111.
- [26]Jung S,Park O J,Kim A R,et al.Lipoteichoic acids of lactobacilli inhibit Enterococcus faecalis biofilm formation and disrupt the preformed biofilm[J].Journal of Microbiology,2019,57(4):310-315.
- [27]Djadouni F,Kihal M.Antimicrobial activity of lactic acid bacteria and the spectrum of their biopeptides against spoiling germs in foods[J].Brazilian Archives of Biology and Technology,2012,55(3):435-444.
- [28]Yépez A,Luz C,Meca G,et al.Biopreservation potential of lactic acid bacteria from Andean fermented food of vegetal origin[J].Food Control,2017,78:393-400.
- [29]Asare P T,Greppi A,Stettler M,et al.Decontamination of minimally-processed fresh lettuce using reuterin produced by Lactobacillus reuteri[J].Frontiers in Microbiology,2018,9:1421.
- [30]Muccilli S,Restuccia C.Bioprotective role of yeasts[J].Microorganisms,2015,3(4):588-611.
- [31]He Yan,Degraeve P,Oulahal N.Bioprotective yeasts:potential to limit postharvest spoilage and to extend shelf life or improve microbial safety of processed foods[J].Heliyon,2024,10(3):24929.
- [32]Du Xiaolong,Li Shaobin,Luo An,et al.Evaluating the fungal pathogens' inhibition efficiency of composite film combined with antagonistic yeasts and sodium alginate on peach[J].Coatings,2023,13(2):417.
- [33]程雷.两种酵母对“红富士”苹果采后病害的生物防治研究[D].南京:南京农业大学食品科学,2010.
- [34]刘程惠,吴祎男,胡文忠,等.苹果腐败霉菌的拮抗酵母菌筛选鉴定及拮抗机理初探[J].食品工业科技,2018,39(12):132-136,163.
- [35]李鑫.饲料加工、贮存及几种添加剂对益生菌活力的影响[D].哈尔滨:东北农业大学,2011.
- [36]何若天.益生芽孢杆菌在水产养殖中的作用和使用方法[J].科学种养,2011(6):4-5.
- [37]Babenko L R,Lazarenko L M,Shynkarenko L M,et al.The effect of lacto- and bifidobacteria in monoculture on the vaginal microflora in norm and in cases of intravaginal staphylococcosis[J].Mikrobiolohichny Zhurnal,2013,75(3):46-55.
- [38]王亚军,王露,王德培.等离子体诱变选育解淀粉芽胞杆菌BI2高产抑菌物质[J].饲料工业,2015,36(1):43-46.
- [39]潘虹余,金玮鋆,张晓蒙,等.解淀粉芽孢杆菌B15抑菌物质对葡萄灰霉病灰葡萄孢的抑菌机理[J].微生物学报,2018,58(7):1245-1254.
- [40]蒋利亚,兰时乐.曲酸生产与利用的研究进展[J].安徽农业科学,2012,40(21):11059-11063.
- [41]Jamal Q,Cho J Y,Moon J H,et al.Identification for the first time of cyclo (D-Pro-L-Leu) produced by Bacillus amyloliquefaciens Y1 as a nematocide for control of Meloidogyne incognita[J].Molecules,2017,22(11):1839.
- [42]Kim C,Jung H,Kim Y O,et al.Antimicrobial activities of amino acid derivatives of monascus pigments[J].FEMS Microbiology Letters,2010(1):117-124.
- [43]张红林.福建古田红曲米天然产物的分离纯化、结构鉴定与活性研究[D].厦门:集美大学,2018.
- [44]陈骐,刘书渊,杨晓暾,等.红色红曲霉Mr-1的次级代谢产物生物活性成分分析[J].微生物学通报,2021,48(3):787-796.
- [45]Mokoena M P.Lactic acid bacteria and their bacteriocins:classification,biosynthesis and applications against uropathogens:a mini-review[J].Molecules,2017,22(8):1255.
- [46]Varsha K K,Devendra L,Shilpa G,et al.2,4-Di-tert-butyl phenol as the antifungal,antioxidant bioactive purified from a newly isolated Lactococcus sp.[J].International Journal of Food Microbiology,2015,211:44-50.
- [47]Le Lay C,Coton E,Le Blay G,et al.Identification and quantification of antifungal compounds produced by lactic acid bacteria and propionibacteria[J].International Journal of Food Microbiology,2016,239:79-85.
- [48]Yu Xiaoyan,Zhang Kuan,Liu Jiayi,et al.Identification and evaluation of an endophytic antagonistic yeast for the control of gray mold (Botrytis cinerea) in apple and mechanisms of action[J].Food Microbiology,2024,123:104583.
- [49]Zhang Xiaokang,Li Boqiang,Zhang Zhanquan,et al.Antagonistic yeasts:a promising alternative to chemical fungicides for controlling postharvest decay of fruit[J].Journal of Fungi,2020,6(3):158.
- [50]Ma Yue,Wu Mengjie,Qin Xiaojie,et al.Antimicrobial function of yeast against pathogenic and spoilage microorganisms via either antagonism or encapsulation:a review[J].Food Microbiology,2023,112:104242.
- [51]Parafati L,Vitale A,Restuccia C,et al.Biocontrol ability and action mechanism of food-isolated yeast strains against Botrytis cinerea causing post-harvest bunch rot of table grape[J].Food Microbiology,2015,47:85-92.
- [52]Leyva S M,Mounier J,Valence F,et al.Antifungal microbial agents for food biopreservation—a review[J].Microorganisms,2017,5(3):37.
- [53]Gómez N C,Ramiro J M P,Quecan B X V,et al.Use of potential probiotic lactic acid bacteria (LAB) biofilms for the control of Listeria monocytogenes,Salmonella typhimurium,and Escherichia coli O157∶H7 biofilms formation[J].Frontiers in Microbiology,2016,7:863.
- [54]Lin Yilin,Wang Ruifei,Li Xiaoqing,et al.Antibacterial mechanism of kojic acid and tea polyphenols against Escherichia coli O157∶H7 through transcriptomic analysis[J].Food Science and Human Wellness,2024,13(2):736-747.
- [55]Settanni L,Franciosi E,Cavazza A,et al.Extension of Tosela cheese shelf-life using non-starter lactic acid bacteria[J].Food Microbiology,2011,28(5):883-890.
- [56]杨旭.新型生物保鲜剂在食品微生物防控中的应用[J].中外食品工业,2024(18):34-36.
- [57]韩千慧,岳琪琪,吴忌,等.曲酸对冷鲜鸭肉腐败微生物致腐能力的影响研究[J].食品科技,2020,45(4):344-350.
- [58]李宏双,孟春玲.食品微生物的抗菌特性在食品防腐中的应用[J].现代食品,2025(4):85-87.
- [59]余诗雨,刘育坚,杨怡,等.曲酸的液相色谱分离方法研究及其在化妆品分析中的应用[J].化学研究与应用,2020,32(9):1724-1727.
- [60]Saeedi M,Eslamifar M,Khezri K.Kojic acid applications in cosmetic and pharmaceutical preparations[J].Biomedicine & Pharmacotherapy,2019,110:582-593.
- [61]Brtko J.Biological functions of kojic acid and its derivatives in medicine,cosmetics,and food industry:insights into health aspects[J].Archiv Der Pharmazie,2022,355(10):2200215.
- [62]Agirman B,Carsanba E,Settanni L,et al.Exploring yeast-based microbial interactions:the next frontier in postharvest biocontrol[J].Yeast,2023,40(10):457.
- [63]Yu Xiaoyan,Zhang Kuan,Liu Jiayi,et al.Identification and evaluation of an endophytic antagonistic yeast for the control of gray mold (Botrytis cinerea) in apple and mechanisms of action[J].Food Microbiology,2024,123:104583.
- [64]Alimadadi N,Pourvali Z,Nasr S,et al.Screening of antagonistic yeast strains for postharvest control of Penicillium expansum causing blue mold decay in table grape[J].Fungal Biology,2023,127(3):901-908.